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Nutrition & Health State
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PMS
Premenstrual syndrome (PMS) is a group of symptoms related to the menstrual cycle that usually occur in the week or two weeks before menstruation. Although the precise cause of PMS is unclear, it has been suggested that the overproduction of pro-inflammatory compounds (eicosanoids) may contribute to PMS. Dietary changes and nutritional supplementation may help with effective management of PMS symptoms.
Related Drugs

Antidepressants
Related Health Topics

Depression ( or Mood disorder)
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If no prescription medications are being used, the following supplements may be beneficial for this health state. If prescription medications are being used, please see the drug-interaction database before making recommendations.
A daily multivitamin will help ensure adequate intake of all essential nutrients and promote overall health and well-being.
Calcium

1200-1600 mg/day. Calcium supplementation may help with some symptoms of PMS. There is evidence that abnormalities in calcium and vitamin D regulation may contribute to the causation of PMS.
Magnesium

200-400 mg/day. Magnesium may help in alleviating PMS symptoms.
Vitamin B6

50-100 mg/day. Additional vitamin B6 may be beneficial in the management of PMS symptoms and premenstrual depression. Dosages should not exceed 100mg/day over a long period of time due to possible toxic effects on the nervous system, causing nerve damage. For long-term use, a daily dosage of 50 mg is considered safe.
Vitamin D

400 IU/day. Vitamin D supplementation may help with some symptoms of PMS. There is evidence that abnormalities in calcium and vitamin D regulation may contribute to the causation of PMS.
Vitamin E

200-400 IU/day. Supplementing with vitamin E may help reduce some PMS symptoms such as anxiety, craving, and depression.
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Currently, there are no known supplements listed on this site that are contraindicated with this health state. There may be interactions between certain vitamins, minerals, supplements, or herbs with prescription medications used for this health concern. View the drug interaction section for more information.

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