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Drug-Nutrient Interactions & Depletions Table

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Iron
Iron is an essential part of hemoglobin, the protein substance which enables red blood cells to carry oxygen through the body.
Benefits
  • Carries oxygen throughout the body
  • Fights the symptoms of anemia
  • Iron boosts energy
Precautions
  • Iron supplements are not recommended for adults over the age of 50 since iron needs decrease with age.
  • Iron supplements are recommended for those who are iron deficient and pregnant and lactating women.
Drug Nutrient Interactions
Recommended Icon
Current research does not indicate that this supplement should be taken to avoid depletions when taking any of the drug categories included in this table.
RX recommended Icon
Anemia

Almost all patients will require iron supplementation for increased erythrocyte development. Prior to and during therapy with an epoetin alfa agent, the patient's iron status including transferrin saturation and serum ferritin should be monitored. Based on a physician's recommendation, iron supplementation is often necessary.
Caution icon
Antibiotics

Iron salts can decrease the absorption of fluoroquinolone and tetracycline antibiotics. Advise patients to take tetracyclines or fluoroquinolones at least 2 hours before, or four to six hours after iron supplements.
Anticoagulants / Antiplatelet Drugs

Caution patients of increased risk of stomach upset or other GI symptoms when combining iron supplements with aspirin or NSAIDs.
Osteoporosis Medications

Divalent cations (eg calcium, iron, etc) can significantly decrease the oral bioavailability of the bisphosphonates (Fosamax, Actonel, Boniva) if taken concurrently. Caution patients not to take iron supplements for at least one to two hours after their bisphosphonate medication.
Avoid icon
Current research does not indicate that this supplement should be avoided when taking any of the drug categories included in this table.

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