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	Wellness Wheel Nutrition & Health States Tables Drug-Nutrient Interactions & Depletions Table Supplement Dosage Chart Herbal Dosage Chart

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Melatonin

Helps promote sleep.


	Benefits Aids in recovery from jet lag. Helps healthy sleep patterns. Promotes restful sleep.			Precautions Do not take melatonin while operating a motor vehicle or machinery. Do not use melatonin if you have an auto-immune condition, depressive or endocrine disorder, or are pregnant or lactating. If no results are seen from melatonin, discontinue its use. If you are under medical supervision, or are taking tranquilizers or sedatives, seek the advice of your physician prior to using melatonin. Keep out of reach of children. Not to be taken by individuals under the age of 16.

Drug Nutrient Interactions

Current research does not indicate that this supplement should be taken to avoid depletions when taking any of the drug categories included in this table.

Current research does not indicate that this supplement provides additional therapeutic benefit's when taking any of the drug categories included in this table.

Antidepressants

Melatonin may interact with medications that inhibit serotonin reuptake including a number of antidepressant medications (SSRIs, tricyclic antidepressants, venlafaxine, etc). Use melatonin with caution if taking antidepressants.

Anxiolytics (antianxiety drugs, sedative-hypnotics)

Melatonin may increase drowsiness and sedation when combined with benzodiazepines or other sedative-hypnotic medications. Advise patient to avoid this combination or use with caution until the effects of this combination on mental acuity or physical ability are determined.

Oral Hypoglycemics (Antidiabetic Drugs)

Melatonin may decrease glucose utilization and increase insulin resistance and thus potentially decrease the therapeutic benefit of antidiabetic drugs. Monitor blood glucose levels closely and adjust dose or discontinue melatonin supplements if necessary.

Narcotic Analgesics

Melatonin may increase drowsiness and sedation when combined with other drugs that produce sedative effects including opioid narcotics. Caution patients about potential increased drowsiness if using this supplement with opioid narcotic drugs.

Antihypertensive Drugs (Calcium Channel Blockers)

Melatonin may impair the efficacy of some calcium channel blockers (nifedipine). Monitor for changes in therapeutic efficacy of CCBs and adjust doses as necessary or avoid use of melatonin with this class of drugs.

Asthma Medications

One of the effects of melatonin is to stimulate certain aspects of immune function; it is not known if or how this action may affect the action of the immunosuppressant / antiinflammatory glucocorticoid steroids. Use with caution in patients being treated for asthma and consult with an MD before using.

Current research does not indicate that this supplement should be avoided when taking any of the drug categories included in this table.

Nutrition and Health State

There may be interactions between certain vitamins, minerals, supplements, or herbs with prescription medications used for this health state. View the drug interaction section for more information.

Metabolic Syndrome

Melatonin may decrease glucose utilization and increase insulin resistance and therefore could interfere with blood sugar control.

Depression ( or Mood disorder)

Melatonin may interact with medications that inhibit serotonin reuptake including a number of antidepressant medications (SSRIs, tricyclic antidepressants, venlafaxine, etc).

Chronic Pain/Chronic Back Pain

Melatonin may increase drowsiness and sedation when combined with other drugs that produce sedative effects including the opioid narcotics.

Muscle Pain (e.g. Fibromyalgia)

Melatonin may increase drowsiness and sedation when combined with other sedative or hypnotic substances or drugs.

Dysmenorrhea

Melatonin may increase drowsiness and sedation when combined with other sedative or hypnotic substances or drugs.

Osteoarthritis

Melatonin may increase drowsiness and sedation when combined with other sedative or hypnotic substances or drugs.

The dietary supplement information contained on this site has been compiled from published sources thought to be reliable, but it cannot be guaranteed. Efforts have been made to assure this information is accurate and current. However, some of this information may be purported or outdated due to ongoing research or discoveries. The authors, editors and publishers cannot accept responsibility for errors or omissions or for any consequences from applications of the information in this site and make no warranty, expressed or implied, with respect to the contents herein.